Benefits

Key Benefits of Our Pharmaceutical Filling Solutions

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Most Advanced Aseptic Filling Technology

BFS technology is considered one of the most advanced aseptic filling technologies, as it eliminates contamination risks.

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Regulatory Compliance

Our bottelpack filling machines comply with the pharmaceutical industry's strictest standards, including Annex 1 of the EU GMP guidelines, and meet regulatory requirements from leading authorities such as EMA, FDA, Anvisa, and Abrasp.

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Efficiency through Automated Filling Process

By automating the entire filling process from container creation to filling and sealing, our filling machines ensure high output and precision while minimizing the risk of errors.

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Flexible Container Design

Our BFS technology offers unparalleled flexibility, enabling single-dose, multi-dose, and specialized container designs like Luer-Lock systems to meet diverse pharmaceutical applications.

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Excellent Barrier Properties

With our multilayer BFS containers, we achieve excellent barrier properties to protect sensitive pharmaceuticals from environmental factors.

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60+ Years of Proven Reliability

For over 60 years, our bottelpack machines have set the industry benchmark for reliability. Many systems have operated consistently since their installation decades ago, underscoring their durability and long-term value.

Pharma applications

The Perfect Packaging for Every Pharmaceutical Application

  • Practical single ampoules
  • Single ampoules with grip grooves
  • Ampoule with resealable protective cap
  • Ampoule as fda certified multidose
  • Multidosis-Ampulle

Ophthalmics

Sterile Blow-Fill-Seal ampoules made of high-quality, recyclable low-density polyethylene (LDPE) are the ideal primary packaging for ophthalmic products, suitable for both single and multiple use. They meet the highest standards in user-friendly handling, format flexibility, product protection, and comply with regulatory requirements such as USP <771>.

Unit-Dose (Typically 0.1-1ml)

  • Up to 33,300 ampoules per hour
  • Preservative-free
  • Easy-to-open twist-off cap
  • Easy to dispense

Multi-Dose (Typically 1-15ml)

  • Up to 12,000 ampoules per hour
  • With or without preservatives
  • Closable, tamper-proof closure
  • Ampoules with bottlepack label
  • Single ampoules with calibrated luer system
  • Single ampoules ventilated luer system

Injections

Our recyclable LDPE or polypropylene (PP) ampoules are specifically engineered for small-volume injectables ranging from 1 to 20 ml. They enable the filling of even demanding pharmaceutical products with sensitivities to heat, light, or oxygen and fulfill regulatory requirements such as USP <790> and <1790>.

  • Up to 33,300 vented or 20,000 calibrated ampoules per hour
  • Luer or twist-off closures for easy and safe use
  • Calibrated Luer ampoules collapse during the process, preventing air ingress and contamination.
  • Terminally sterilizable
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  • Nipplehead bottle
  • Various caps on ampoules
  • Bottle with integrated volume displacement
  • Different bottle volumes

Infusions

The unbreakable, lightweight, and terminally sterilizable BFS infusion bottles are the superior packaging choice for infusion products. They can be vented or unvented and feature an integrated suspension device for versatile use.

  • Up to 10,000 bottles per hour
  • Various container geometries in the 50-1000 ml range
  • Optimized for effective product withdrawal even without ventilation due to the collapsing design of the infusion bottle
  • Product withdrawal through caps with an infusion port (Euro head) or nipple head.
  • Ampoules with screw cap
  • Small round ampoules
  • Ampoule block with inhalation solution Device
  • Labeling in hot stamping

Inhalation Solutions

Pharmaceutical products used in inhalers or nebulizers are safely protected in sterile BFS ampoules. With a user-friendly twist-off cap and soft LDPE material, our ampoules provide safe, convenient dosing for patients. Whether you need single doses starting at 0,25 ml or closable multi-doses up to 5 ml, we’ve got you covered.

  • Up to 33,300 ampoules per hour
  • Single or Multi-Dose
  • Flexible in geometry, e.g. ampoules can be directly inserted into inhalation devices

BFS: The Perfect Filling Solution for a Wide Range of Pharmaceutical Products

BFS is the perfect fit for your product if:

  • Your filling volume ranges from 0.1ml to 1000 ml
  • You need sterile single- or multi-dose products
  • You want to rely on proven container designs
  • You require vented or unvented containers
  • Custom forms and functions are necessary for your product
  • Terminal sterilization is required
  • Your formulation must be free from preservatives
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BFS Produkt-Check Pharma

Möchten Sie etwas tiefer einsteigen und herausfinden, ob BFS für Ihr pharmazeutisches Produkt geeignet ist? Laden Sie unseren umfassenden BFS-Produktcheck herunter, um die Kompatibilität mit Ihren spezifischen Anforderungen zu prüfen.

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Partner for the pharmaceutical industry

More Than a Machine Supplier – Your Comprehensive Partner for the Pharmaceutical Industry

At Rommelag, we do more than manufacture industry-leading filling machines—we partner with you to bring your pharmaceutical products to life. As both a pioneering filling machine manufacturer and a trusted contract filler, we offer seamless, end-to-end solutions that support your needs at every stage of product development. Whether you're looking for a bottelpack filling machine or leverage our extensive contract filling and product development services (CDMO), Rommelag stands ready as your one-stop partner for success.